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Chemical Engineer with extensive biotechnology experienceR&D Services: Chemistry, BiotechnologyLegal Services: Patent Services, Evidence Evaluation-technicalChemical Engineering: Process Troubleshooting, Process DevelopmentScale-up in bulk chemicals and dosage formsValidation in Manufacturing: Qualification of facilities and equipment IQ/OQ/PQIndependent Evaluations: manufacturing. processes, environment, safety, patents, waste management.Foster Wheeler, Chief EngineerScaleup of blood fractionation plant.Design comparisons for domestic and international plants.Safety audits and HAZOP...
Consultant bioengineer expert in biomaterial science, nanotechnology, biosynthesis of polymeric biomaterials for implants and drug delivery.Synthesis of biomaterials and biomineralization, wherein a living organism provides an environment that controls the nucleation and growth of unique mineral phases.Synthesis and characterization of self-assembly of block copolymers.Nanostructured composites and polymeric biomaterials production and analysis.Consulting on artificial implants, drug delivery systems and medical devices
Molecular biophysics with expetise in development of novel biomimetic ligands.Biomimetic ligand design and characterization, biomolecular recognition.Expert and consultant in molecular biophysics.Skilled in surface chemistry, colloid chemistry and nanoscale particle synthesis.Polymer physical chemistry and synthesis of collodial systems.Molecular, nanoscale to microscale applications.Drug development process (NDA%u2019s. IND%u2019s).Applied analytical methods %u2013 Nuclear Magnetic Resonance, High Pressure Liquid Chemistry, Mass Spectrometry.Scientific Translation: Fluent in German, Swedish and English.
Expert and Consultant on Green-Fluorescent Protein: Isolation, Assay Development and Biochemistry of Bioluminescence and Luminescent SystemsGreen-fluorescent protein (GFP): isolation and characterizationMarine bioluminescenceElectrophoresisGFP in HTS assay developmentBiochemistry of luminescent systemsProtein and peptide chemistry including isolation and purificationBatch methods of protein purification such as tangential flow ultra filtration and three-phase partitioning.Protein photoinactivationHPLCBioluminescent genetic assay developmentProtease assay developmentAssay design and diagnostics kits.
International expert researches polymers from renewable resources using biomass, cellulose fibers, starch, lignins, chitosan, suberin, furans and vegetable oilsBiomass conversion into bio chemicals and bio polymers.Polymers and copolymers bearing furan heterocycles.Chemical modification of cellulose.Lignins and lignin derivatives and additive or macromonomers for polymers.Oxypropylation of natural polymers to give polyols for polymer synthesis.Chemical modification of starches.Chemical exploitation of suberin.Photosensitive polymers from vegetable oils.Chemical modifications of polymeric surfaces.Polymers from renewable resources.Composit...
Expert consulting on mammalian and bacterial cell bioprocess, cell cultivation, cell purification and cell characterization.Cell culture/bioprocess, protein expression, protein purification, and surface sciences.Significantly improved recombinant protein yields (>10x to >1 g/L) in E. coli cultures by rational medium design and bioprocess optimization.Extensive cell culture experience for a wide range of cell types (e.g. mammalian cell lines, primary cells, bacteria and fungi).Specialized in cell selection, cultivation, characterization and recovery.Protein purification processes and protein purification strategies.Expertise spans from upst...
Consultant on Human Cell R&D, Cell Culture, and Production of Mammalian CellsCulture of established cell lines (attached or in suspension) for production of biologicals, such as CHO cells and hybridomas.Design and optimization of cell culture media with emphasis on the development of animal component-free formulations for biopharmaceutical applications.Scale up and process optimization of mammalian cell cultures from research and development to pilot production.Application of design of experiment software to the development, scale up and optimization of cell culture processes for increased productivity and reduced costs.Research and devel...
Protein Chemistry Consultant Specializing in Protein Purification, Characterization, Analysis, Research and Protein DevelopmentDeveloped novel procedures for purification of proteins from recombinant sources including: bacteria, yeast, mammalian cells and viral expression systems.Purified recombinant proteins containing affinity tags such as six-histidine and glutathione transferase; published new procedure for purification of c-myc tagged proteins by immuno-affinity chromatography.Large-scale production of native proteins from animal tissue and blood products.Developed two commercial products for clinical diagnostics market.Isolated and...
GMP Biochemistry Consultant and Laboratory Manager in CanadaOver fourteen years in the Canadian life science industry specifically in biopharmaceutical GMP development and manufacturing.Directed major operational departments including quality assurance, quality control, validation, operations, process development and project management.For start-up company established operational departments, internal business systems, annual budgeting, personnel management and mentoring, contract estimation, contract negotiation, contract management and quality oversight, all within the highly regulated GMP manufacturing environment.CMC commercial portfo...
Fermentation and Biotechnology Expert with Biofuels and Biochemicals ExperienceFermentation and biotechnology.Fermentation of biofuels and biochemical.Scale up and technology transfer of enzyme production.Biotransformation.Production and expression of recombinant proteins through fermentation.Conversion of biomass to ethanol.Independent Consultant, PresentDuPont Corporation, Research, 1994 - PresentProjectsProduction and expression of recombinant proteins through fermentation.Scale up and technology transfer of enzyme production.Extractive fermentation of tolu...