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Pharmaceutical Chemist Consultant: Drug Discovery and Drug Portfolio Management With Global Pharmaceutical Companies

Technical Consultant #1571


Expertise

  • Drug discovery and innovation management with global pharmaceutical companies.
  • Create and implement pharmaceutical research and development strategies and processes to deliver superior value.
  • Develop and implement worldwide pharmaceutical portfolio management for GlaxoSmithKline discovery and genetics research businesses.
  • Negotiations and implementation of processes for selection and prioritization of drug research programs.
  • Enabled the increased productivity of drug leads in GSK by 50% in 2 years and reduced cycle times by 50%.

Experience

GlaxoSmithKline, 2000 - 2008

Molecular Discovery Research Portfolio Management

  • Developed and implemented worldwide Portfolio Management for GlaxoSmithKline discovery and genetics research businesses encompassing 2000 staff people and $400 million budget.
  • Developed and managed process involving: Negotiation and implementation of processes for selection and prioritization of research programs; developing IT modeling systems to present performance with fit-for-purpose benchmarking analysis; modeling future performance; and, change management and team training.
  • Increased in productivity of drug-like leads in GSK by 50% in 2 years.

Director, Genetics and Discovery Research Portfolio Management, 1998 - 2000

Director, Discovery Research Portfolio Management, 1992 - 1998

SmithKline Beecham, King of Prussia, PA, 1989 - 2000

Discovery Portfolio Management, Director

Associate, Director, Medicinal Chemistry

  • Discovered and championed lotrafiban (antithrombotic) to Phase III and 2 preclinical candidate antithrombotics.
  • Leader in diverse areas of drug discovery - small molecule, peptidomimetic and peptidic therapies for HIV, osteoporosis, restenosis, thrombosis and hypertension.

Beckman Instruments, Palo Alto, CA, Principal Research Chemist, 1977 - 1989

  • Peptide Chemistry: Leader in diverse areas of drug discovery with small molecule, peptidomimetic and peptidic therapies for pain and hypertension.

Massachusetts Institute of Technology, Cambridge, MA, Postdoctoral Chemist,1975 - 1977

  • Developed new synthetic organic chemical methodologies.

Honors & Publications


Academic and Professional Affiliations

  • Project Management Institute
  • The American Chemical Society
  • The American Association for the Advancement of Science
  • The American Peptide Society

Certifications and Credentials

  • Co-Principal Investigator, N.I.H. PO1 grant in collaboration with Harvard, Columbia and Penn to develop novel AIDS therapies.
  • Editorial Advisory Board, Drug Design and Discovery
  • NIH Biochemistry Study Section

Patents and Publications

  • Over 25 patents.
  • Over 75 papers and invited speaker at over 25 conferences and symposia.

Education

  • Ph.D. Organic Chemistry, University of Michigan, Ann Arbor, MI
  • B.S. Organic Chemistry, Kalamazoo College, Kalamazoo, MI
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