Biomolecular Physicist Consultant: Development Novel Biomimetic Ligands (1224)
Expertise
Biomimetic ligand design and characterization, biomolecular recognition.
Expert and consultant in molecular biophysics.
Skilled in surface chemistry, colloid chemistry and nanoscale particle synthesis.
Polymer physical chemistry and synthesis of collodial systems.
Molecular, nanoscale to microscale applications.
Drug development process (NDA%u2019s. IND%u2019s).
Applied analytical methods %u2013 Nuclear Magnetic Resonance, High Pressure Liquid Chemistry, Mass Spectrometry.
Scientific Translation: Fluent in German, Swedish and English.
Experience
Consultant in molecular biophysics and biomimetic ligand design
Chief Scientific Officer and Cofounder of startup company focused on the design and commercialization of novel, conformationally flexible affinity ligands, eg., self-reporting chips for nucleic acid applications
Visiting Scientist, Center for Applied Genomics, Public Health Research Institute, Newark, NJ. Coinventor of novel molecular beacons technologies for self-reporting, chip-based assays.
Visiting Scholar, Rutgers University, Piscataway, NJ: Performed basic and applied studies of biomimetic ligand conformational transitions.
Director, Biophysics Research, Transgenomic, Inc., Piscataway, NJ: Developed biophysical applications of variable temperature HPLC; Designed and tested novel biomimetic ligands
Principal Scientist, GelTex/Genzyme Pharmaceuticals, Waltham, MA: Provided physical chemical rationale for the biological properties of bile acid sequestrants, toxin binders, fat binders, lipase inhibitors, and other polymeric drugs
Associate Professor, Dept of Chemistry, University of Nebraska, Lincoln, NE: Ion effects on nucleic acid conformation and dynamics; structure and molecular recognition of signal transducing peptides in lipid environments
Honors & Publications
Numerous patents and publications
Education
Ph. D., Physical Chemistry, University of Wisconsin, Madison, Wisconsin
B. S., Chemistry, Antioch College, Yellow Springs, Ohio