Expertise

Biomedical Scientist with experience in:

• Wound dressing.
• Transdermal and topical drug delivery systems.
• Drug delivery systems.
• Conductive adhesives.
• Medical electrodes.
• Hard and soft tissue adhesives.
• Cardiovascular, urinary tract and orthopedic implants.
• Dental materials.

Broad background in polymer chemistry and technology:

• Hydrogels.
• UV and E-Beam radiation grafting and crosslinking.
• Water soluble polymers.
• Monomer/polymer synthesis.
• Structural property relationships.
• Chemical vulcanization.

Experience

Independent Consultant, 1997 - Present

Undisclosed Firm, Director New Product Development and Regulatory Affairs

• Developed new conductive adhesive hydrogels for use in medical electrodes for neuromuscular stimulation applications.
• Provided technical expertise in expediting all materials related problems:
• Identified biomedical extrusion grade polyurethane rubbers for lead wire manufacturing.
• Identified improved hot melt adhesives for electrode assembly.
• Prepared and filed 510(k) submissions.

Cambrex Hydrogels, Harriman, NY, 1989 - 1995

Polymer Research and Development Manager

• Hired, trained and supervised a staff of 5 scientists and technicians.
• Developed customer-oriented research projects designed to meet or exceed customer requirements and expedite project cycle time.
• Met corporate goals for Total Quality Management through a complete re-evaluation of all research and development and G.C. procedures for raw materials, intermediates and products using various statistical methods including Statistical Process Control (SPC).
• Established SPC as a management technique to improve product quality and manufacturing efficiency and furthered adoption of cGMP's.
• Filed 5 patents of which 3 have issued and 2 were abandoned by the new owners.
• Saved a $750,000 electrically conductive hydrogel as the result of process and product improvements.
• Initiated and managed a 14-month program in transdermal and topical drug delivery that included outside research contract.
• Established the utility of monolithic hydrogel delivery systems and identified new hydrogel compositions for site-specific oral drug delivery.
• Discovered a new class of high adhesion electro-conductive hydrogels.
• Conceived and implemented a project to develop a flowable gel deep cavity wound dressing based on interpenetrating polymeric networks.

Vice President, Research and Development

• Solved problems associated with the development of a family of polypeptide based tissue adhesives for dermal wounds, reconstructive surgery and ophthalmology.
• Reorganized the 18-member research group into teams to concentrate on basic problems inherent in the core technology.
• Established product and process control protocols for identification of key problems associated with earlier synthetic analogues of the mussel adhesive.
• Isolated co-factors, possibly contributing to the adhesive character of the mussel adhesive.
• Developed two non-medical applications for this technology, corrosion coatings and metal sequestering.

Valleylab, Inc. Div. Pfizer Hospital Product Group, Boulder, CO, 1984 - 1989

Manager, Technology Development

• Hired, trained and managed a staff of 5 scientists and technicians.
• Managed an intensive program of formulation optimization for process and product development of electro surgical grounding pads and TENS and EKG electrodes.
• Successfully completed the program and transferred the processes to toll manufacturer.
• Successfully defended company's patent applications, which resulted in establishing a proprietary position in their cross linked hydrogen technology.
• Developed hydrogen adhesives for wound/burn dressings.
• Established an exploratory project in transdermal drug delivery system and demonstrated efficacy for analgesic and NSAID containing patches.

Howmedica, Inc., Corporate R&D Lab Div., Pfizer Hospital Products Group, Groton, CT, 1979 - 1984

• As Manager, Technology Development, directed wide-ranging technology assessment project for the Corporate Business Development Group with special emphasis on least invasive surgery.
• Responsible for project planning and financial management for the department.

Manager, Polymer Research from 1979 - 1982.

Myerson Tooth Corp., Howmedica, Inc., Cambridge, MA, 1976 - 1979

• Manager Dental Materials Research

Pennwalt Corp., Flourochemicals & Plastics Div., King of Prussia, PA, 1968 - 1976

• Project Leader

Raychem Corp., Menlo Park, CA, 1966 - 1968

• Staff Scientist

Union Carbide Corp., Chemicals and Plastics Div., Bound Brook, NJ, 1963 - 1966

• Research Chemist

Honors & Publications

Academic and Professional Affiliations

• American Chemical Society
• The Society for Biomaterials
• Member U.S. Delegation of the International Standards Organization, TG-105 Meeting in Berlin, West Germany, WG2 Color Stability and Synthetic Resin Teeth.
• Referee for Papers in Polymer Science in the "Journal of Biomedical Materials Research."
• American National Standards Committee, MD-156, Dental Materials, Instruments and Equipment, Past Chairman of the Plastic Resin Teeth and Plastic Veneering Materials. Sub-committees, ANSC MD-156 Certificate of Appreciation.

Additional Courses

• Hartford Graduate Center, Engineering Management.
• Hartford Graduate Center, Financial and Managerial Accounting.
• American Management Association, Senior Project Management.
• American Management Association, Successfully Managing People.
• Q/P Management Inc., Process Capability Workshop.
• Purdue University, Hydrogens for Medicine and Pharmacy.
• Tempera Total Quality Management (3M) Training Course.
• Tempera GMP Training Course for Bulk Pharmaceutical Manufacturers.
• Pfizer Hospital Products Group Clinical Affairs State- of-the-Art Seminar.
• Pfizer Hospital Products Group Sterilization State-of-the Art Seminar.
• Pfizer Management Course in Negotiating with Superiors and Subordinates.
• Kepner-Tragoe, Decision Making and Problem Analysis.
• Pfizer Management Development Program.
• Dale Carnegie, Human Relations.

Credentials

• Post-Ph.D., Organic Chemistry, Ohio State University

Guest Speaker and Lectures

• Tufts University, School of Dental Medicine, Guest Lecturer on Dental Polymers.
• University of Washington, Bioengineering Center, Seminar Presentation, "The Polymer Chemistry of Denture Fabrication."
• New London County (CT) Dental Society, Guest Speaker, "Research Activities at Howmedica Corporate Research Laboratories."

Publications

• Twenty-two publications and one U.S. patent.

Education

• Ph.D. Organic Chemistry, University of Washington
• B.S. Chemistry with Honors, University of Illinois